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IOBRIX INJ 350

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  • IohexolProduct documentation

    제품상세설명
    DivisionSpecialty drugs
    SymptomsIodine Contrast Media
    Insurance code650100641(10ml) 외 5개

기본정보

복약안내

주의사항

전체정보

MAIN INGREDIENT

Per 1mL
Iohexol (USP) . . . . . . . . . . . .755mg
(as Iodine 350mg)

APPEARANCE

Colorless-to-lemon yellow clear injection in a colorless vial

EFFICACY

- Angiography
- IVP
- Contrast enhancement
- Body cavities: arthrography, gastrointestinal studies

The dosage varies depending on the type of examination, age, weight, cardiac output and general condition of the patient and the technique used. Usually the same iodine concentration and volume is used as with other iodinated X-ray contrast media in current use. Adequate hydration should be assured before and after administration.
The following dosages may serve as a guide:

Indication

Concentration

Volume

Comments

IVP

 

Adults:

Children < 7 kg

Children > 7 kg

 

 

300/350mgI/mL

 

300mgI/mL

 

300mgI/mL

 

 

4080mL

 

1.52mL/kg

 

1.5mL/kg

Volume per injection depends on weight and stature of the patient.

Usual: 6570mL

Usual: 60mL

Max.: 40mL

Phlebography(leg)

240/300mgI/mL

20100mL/leg

DSA

300/350mgI/mL

2060mL/inj

Contrast enhancement

Adults

 

 

Children

 

240mgI/mL

300mgI/mL

350mgI/mL

240mgI/mL

300mgI/mL

 

125250mL

100200mL

100150mL

23mL/kg

13mL/kg

 

3060gI

3060gI

3552.5gI

Max. 40mL

(In a few cases up to 100mL may be given)


 

Indication

Concentration

Volume

Comments

Arteriographies

Arch aortography

Selective cerebral aortography

Femoral

 

 

 

300/350mgI/mL

 

300mgI/mL

 

300mgI/mL

 

 

 

3060mL/inj

(max. 250mL)

510mL/inj

 

3080mL/inj

 

 

 

Avg. 40mL/inj

 

 

 

Aorta femoral artery: select a high side, Direct femoral artery: select a low side

Cardioangiography

 

Adults

Left ventricle & aortic root inj.

Selective coronary arteriography

 

Children

 

 

350mgI/mL

350mgI/mL

 

300/350mgI/mL

 

 

3060mL/inj

1.58mL/inj

 

 

 

 

Max. 250mL when repeat injection indicated.

Depending on age,

weight and pathology

(Max. 46mL/kg)

DSA

240/300mgI/mL

115mL/inj


< Guidelines for Intrathecal use >

Indication

Concentration

Volume

Lumbar & thoracic myelography(lumbar injection)

240mgI/mL

812mL

Cervical myelography(lumbar injection)

240mgI/mL

300mgI/mL

1012mL

710mL

Cervical myelography(lateral cervical injection)

240mgI/mL

300mgI/mL

610mL

68mL

CT cisternography

240mgI/mL

412mL

To minimize possible adverse reactions, a total dose of 3g iodine should not be exceeded.

 

Indication

Concentration

Volume

Comments

Arthrography

 

240mgI/mL

300mgI/mL

350mgI/mL

520mL

515mL

110mL

ERP/ERCP

240mgI/mL

2050mL

Herniography

240mgI/mL

50mL

The dosage varies with the size of the hernia

Hysterosalpingography(HSG)

240mgI/mL

300mgI/mL

1550mL

1525mL

Sialograph

240/300mgI/mL

0.52mL

Gastrointestinal Studies

Adults

 

 

Children

 

 

Children

 

 

 

150/350mgI/mL

 

300/350mgI/mL

 

Dilute with tap water to 100150mgI/mL

 

 

Individualize

 

 

24mL/kg

 

 

510mL/kg

 

 

 

 

 

 

Max. 50mL

 

 

Example: Dilute Iohexol 240, 300 or 350 with tap-water 1:1 or 1:2

Tightly closed, keep at 1~30℃

STRONG POINT

Iodine is a positive contrast medium that exerts by high absorption of radiation.
When Iodine is injected into the vessel, it is absorbed in all tissues, blood cells and extracellular spaces thereby enhance the delineation of blood vessel, organa parenchymatosa and other solid tissues. 
Advantages of IOBRIX INJ 350, a non-ionic, water-soluble contrast media, are as follows:
1) This non-ionic contrast media contains 6 hydroxyl(-OH) groups which give the product their high degree of hydrophilicity. Chemotoxicity and neurotoxicity of IOBRIX INJ 350 is lower than other non-ionic contrast media.
2) Iohexol injection is a world-leading contrast agent and regarded as the “Gold Standard of contrast media.
3) Iohexol has a broad spectrum of indications. (Since iopromide is more neurotoxic than all other contrast media, it is not indicated for intrathecal use. Ioversol is not indicated for body cavities and intrathecal use.)
4) Iohexol has a very low protein binding rate. It has been proven safe and efficient in long-experienced clinical data.

MAIN INGREDIENT

Per 1mL
Iohexol (USP) . . . . . . . . . . . .755mg
(as Iodine 350mg)

APPEARANCE

Colorless-to-lemon yellow clear injection in a colorless vial

EFFICACY

- Angiography
- IVP
- Contrast enhancement
- Body cavities: arthrography, gastrointestinal studies

MEDICATION INFORMATION

The dosage varies depending on the type of examination, age, weight, cardiac output and general condition of the patient and the technique used. Usually the same iodine concentration and volume is used as with other iodinated X-ray contrast media in current use. Adequate hydration should be assured before and after administration.
The following dosages may serve as a guide:

Indication

Concentration

Volume

Comments

IVP

 

Adults:

Children < 7 kg

Children > 7 kg

 

 

300/350mgI/mL

 

300mgI/mL

 

300mgI/mL

 

 

4080mL

 

1.52mL/kg

 

1.5mL/kg

Volume per injection depends on weight and stature of the patient.

Usual: 6570mL

Usual: 60mL

Max.: 40mL

Phlebography(leg)

240/300mgI/mL

20100mL/leg

DSA

300/350mgI/mL

2060mL/inj

Contrast enhancement

Adults

 

 

Children

 

240mgI/mL

300mgI/mL

350mgI/mL

240mgI/mL

300mgI/mL

 

125250mL

100200mL

100150mL

23mL/kg

13mL/kg

 

3060gI

3060gI

3552.5gI

Max. 40mL

(In a few cases up to 100mL may be given)


 

Indication

Concentration

Volume

Comments

Arteriographies

Arch aortography

Selective cerebral aortography

Femoral

 

 

 

300/350mgI/mL

 

300mgI/mL

 

300mgI/mL

 

 

 

3060mL/inj

(max. 250mL)

510mL/inj

 

3080mL/inj

 

 

 

Avg. 40mL/inj

 

 

 

Aorta femoral artery: select a high side, Direct femoral artery: select a low side

Cardioangiography

 

Adults

Left ventricle & aortic root inj.

Selective coronary arteriography

 

Children

 

 

350mgI/mL

350mgI/mL

 

300/350mgI/mL

 

 

3060mL/inj

1.58mL/inj

 

 

 

 

Max. 250mL when repeat injection indicated.

Depending on age,

weight and pathology

(Max. 46mL/kg)

DSA

240/300mgI/mL

115mL/inj


< Guidelines for Intrathecal use >

Indication

Concentration

Volume

Lumbar & thoracic myelography(lumbar injection)

240mgI/mL

812mL

Cervical myelography(lumbar injection)

240mgI/mL

300mgI/mL

1012mL

710mL

Cervical myelography(lateral cervical injection)

240mgI/mL

300mgI/mL

610mL

68mL

CT cisternography

240mgI/mL

412mL

To minimize possible adverse reactions, a total dose of 3g iodine should not be exceeded.

 

Indication

Concentration

Volume

Comments

Arthrography

 

240mgI/mL

300mgI/mL

350mgI/mL

520mL

515mL

110mL

ERP/ERCP

240mgI/mL

2050mL

Herniography

240mgI/mL

50mL

The dosage varies with the size of the hernia

Hysterosalpingography(HSG)

240mgI/mL

300mgI/mL

1550mL

1525mL

Sialograph

240/300mgI/mL

0.52mL

Gastrointestinal Studies

Adults

 

 

Children

 

 

Children

 

 

 

150/350mgI/mL

 

300/350mgI/mL

 

Dilute with tap water to 100150mgI/mL

 

 

Individualize

 

 

24mL/kg

 

 

510mL/kg

 

 

 

 

 

 

Max. 50mL

 

 

Example: Dilute Iohexol 240, 300 or 350 with tap-water 1:1 or 1:2

NOTES

Tightly closed, keep at 1~30℃